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Tuesday 22 September 2009

Asprin as therapy for colorectal cancer


This is an extract of a paper which states new findings about asprins use in treating
colorectal cancer the full story is in JAMA. 2009;302(6):688-689

Extract

Even before the time of Hippocrates, willow extracts, which contain salicylates, were used in medicine as analgesic, anti-inflammatory, and antipyretic agents. Acetylsalicylic acid was isolated in the mid-19th century, and since 1899 when it was patented, aspirin has enjoyed global popularity. The relatively recent discovery of its antiplatelet activity has also led to the widespread use of aspirin as an antistroke and cardioprotective agent, but the list of its medical applications continues to increase.

More than 30 years ago, Sporn et al2 coined the term chemoprevention to describe and propose the use of oral drugs, chemicals, or supplements to reduce the risk of cancer. In the ensuing decades, chemoprevention research has generated high hopes and enormous increases in funding, although only a few agents have shown efficacy in clinical trials, and of those few, most are too toxic for use by average-risk individuals. In addition...... .

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